TB-500 (Thymosin Beta-4) 10mg

Description

Thymosin beta-4 (Tβ4) is a 43-amino-acid, actin-sequestering peptide found in most mammalian cells. It is supplied here as the acetate salt. OxygenLab supplies TB-500 (Thymosin Beta-4) as a lyophilized powder (10 mg per vial), third-party tested with a batch certificate of analysis.

TB-500 (Thymosin Beta-4) Specifications

Formula, molecular weight and CAS number per PubChem.

Research Overview

Tβ4 is studied for its role in actin regulation, cell migration and angiogenesis, using cell-culture and animal models of wound and tissue-repair biology.

Reviews describe it as a multi-functional regenerative peptide and outline the signalling pathways investigated to date.

Selected Research References

• beta-Thymosins, Ann N Y Acad Sci, 2007.
• Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications, Expert Opin Biol Ther, 2012.

TB-500 (Thymosin Beta-4): Research Background

Thymosin beta-4 was characterised in 1981 from thymosin fraction 5, a calf thymus extract. It is a 43-residue peptide and the main G-actin-sequestering molecule in many cell types.

Its actin-binding activity is centred on the LKKTETQ motif (residues 17–23). Research has studied Tβ4 in cell-migration, angiogenesis and wound models, including corneal, dermal and cardiac tissue; a 2004 Nature paper linked it to integrin-linked kinase signalling in cardiac models.

The N-terminal tetrapeptide Ac-SDKP, released by enzymatic cleavage, is studied separately in fibrosis research.

What the TB-500 (Thymosin Beta-4) COA Confirms

Each batch is tested by an independent laboratory. HPLC reports purity as the main peak’s share of total peak area, and mass spectrometry confirms identity against the expected molecular weight of approximately 4963 g/mol. Batch-specific reports are published on our COAs page; match the lot number on your vial to the report before use in an experiment.

Related Research Compounds

Laboratories working with TB-500 (Thymosin Beta-4) often also reference: BPC-157, GLOW Blend, BPC-157 + TB-500 Blend.

More Questions About TB-500 (Thymosin Beta-4)

What is the actin-binding region of Thymosin Beta-4?

The LKKTETQ motif at residues 17–23.

Why are there 5 mg and 10 mg TB-500 vials?

The compound and testing are identical; the two sizes suit different laboratory batch sizes.

Storage and Handling

• Store lyophilized powder at -20°C for long-term storage, protected from light and moisture.
• Short-term storage at 2–8°C is acceptable for unopened vials.
• Allow the vial to reach room temperature before opening to limit moisture uptake.
• Prepare solutions according to your laboratory protocol and record batch and lot numbers.

Frequently Asked Questions

How is the purity of TB-500 (Thymosin Beta-4) verified?

Each batch is tested by an independent third-party laboratory for identity and purity (HPLC and mass spectrometry). The certificate of analysis is published on our COAs page.

How should lyophilized TB-500 (Thymosin Beta-4) be stored?

Store unopened vials at -20°C, protected from light and moisture. Short-term storage at 2–8°C is acceptable.

Is TB-500 (Thymosin Beta-4) intended for human use?

No. TB-500 (Thymosin Beta-4) is sold strictly for laboratory research use and is not for human or animal consumption.

Related Research Guides

• BPC-157 vs TB-500: a research comparison
• How to read a peptide certificate of analysis
• What HPLC purity means for research peptides
• How to store lyophilized peptides

Research use only. This product is supplied for in-vitro laboratory research and analytical use only. It is not for human or animal use, and not intended to diagnose, treat, cure or prevent any disease. See our Legal & Compliance policy.