Description
CJC-1295 with DAC is a synthetic, long-acting analog of growth-hormone-releasing hormone (GHRH 1-29) with a Drug Affinity Complex that binds serum albumin. OxygenLab supplies CJC-1295 with DAC as a lyophilized powder (2 mg per vial), third-party tested; published certificates are on our COA page.
CJC-1295 with DAC Specifications
| Compound | CJC-1295 with DAC |
|---|---|
| Sequence / structure | Modified GHRH(1-29) analog with a Drug Affinity Complex (maleimidopropionyl-lysine) for albumin binding |
| Molecular formula | C165H269N47O46 |
| Molecular weight | 3647.2 g/mol |
| CAS number | 446262-90-4 |
| Form | Lyophilized powder |
| Amount per vial | 2 mg |
| Purity | Third-party tested by HPLC and MS (COA available on request) |
Formula, molecular weight and CAS number per PubChem.
Research Overview
CJC-1295 is studied in endocrine research on the GHRH receptor and growth-hormone pathway, particularly how albumin binding extends the half-life of GHRH analogs.
The 2006 pharmacology study that characterised its long-acting profile remains the primary reference.
Selected Research References
- Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, J Clin Endocrinol Metab, 2006.
CJC-1295 with DAC: Research Background
CJC-1295 is a modified version of GHRH(1-29), the shortest fully active fragment of growth-hormone-releasing hormone. Amino acid substitutions were introduced to resist cleavage by dipeptidyl peptidase-4, which rapidly inactivates native GHRH.
The Drug Affinity Complex (DAC) is a reactive maleimide linker on a lysine residue that binds covalently to serum albumin. In the 2006 pharmacology study this albumin binding extended the analogue’s half-life to several days, compared with minutes for native GHRH.
CJC-1295 is therefore used as a reference compound in research on half-life extension through albumin conjugation, a strategy also studied for other peptides.
What the CJC-1295 with DAC COA Confirms
OxygenLab products are tested by independent third-party laboratories. HPLC reports purity as the main peak’s share of total peak area, and mass spectrometry confirms identity against the expected molecular weight of 3647.2 g/mol. Published certificates are on our COA page, and others are available on request; match the lot number on your vial to the report before use in an experiment.
Related Research Compounds
Laboratories working with CJC-1295 with DAC often also reference: AOD-9604.
More Questions About CJC-1295 with DAC
What does DAC stand for?
Drug Affinity Complex, a maleimide-based linker that lets the peptide bind covalently to serum albumin.
Which hormone is CJC-1295 based on?
Growth-hormone-releasing hormone, specifically its 1-29 fragment.
Storage and Handling
- Store lyophilized powder at -20°C for long-term storage, protected from light and moisture.
- Short-term storage at 2–8°C is acceptable for unopened vials.
- Allow the vial to reach room temperature before opening to limit moisture uptake.
- Record batch and lot numbers for every preparation.
Frequently Asked Questions
How is the purity of CJC-1295 with DAC verified?
OxygenLab products are tested by independent third-party laboratories for identity and purity (HPLC and mass spectrometry). A certificate for this product is available on request; contact us. Published certificates are on our COA page.
How should lyophilized CJC-1295 with DAC be stored?
Store unopened vials at -20°C, protected from light and moisture. Short-term storage at 2–8°C is acceptable.
Is CJC-1295 with DAC intended for human use?
No. CJC-1295 with DAC is sold strictly for laboratory research use and is not for human or animal consumption.
Related Research Guides
- How to read a peptide certificate of analysis
- What HPLC purity means for research peptides
- How to store lyophilized peptides
Research use only. This product is supplied for in-vitro laboratory research and analytical use only. It is not for human or animal use, and not intended to diagnose, treat, cure or prevent any disease. See our Legal & Compliance policy.











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