Description
Epithalon (Epitalon) is a synthetic tetrapeptide modelled on a pineal-gland peptide extract. OxygenLab supplies Epithalon as a lyophilized powder (10 mg per vial), third-party tested; published certificates are on our COA page.
Epithalon Specifications
| Compound | Epithalon |
|---|---|
| Sequence / structure | Ala-Glu-Asp-Gly (tetrapeptide) |
| Molecular formula | C14H22N4O9 |
| Molecular weight | 390.3 g/mol |
| CAS number | 307297-39-8 |
| Form | Lyophilized powder |
| Amount per vial | 10 mg |
| Purity | Third-party tested by HPLC and MS (COA available on request) |
Formula, molecular weight and CAS number per PubChem.
Research Overview
Epithalon is studied in cellular-ageing research, particularly telomerase activity and telomere length in human cell lines.
A 2025 review summarises the biochemical properties and research findings reported for this peptide.
Selected Research References
- Overview of Epitalon: Highly Bioactive Pineal Tetrapeptide with Promising Properties, Int J Mol Sci, 2025.
- Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity, Biogerontology, 2025.
Epithalon: Research Background
Epithalon (Ala-Glu-Asp-Gly, also spelled Epitalon) was developed by Vladimir Khavinson’s group at the St. Petersburg Institute of Bioregulation and Gerontology. It was designed as a synthetic analogue of epithalamin, a peptide extract of the pineal gland.
The most-cited laboratory work examines telomerase activity and telomere length in cultured human cells, including fibroblast cell lines. Other published studies have looked at pineal melatonin rhythms in aged animal models and at gene-expression changes in cell culture.
Because it is only four residues long, Epithalon is also a convenient model compound for short-peptide stability and analytical method development.
What the Epithalon COA Confirms
OxygenLab products are tested by independent third-party laboratories. HPLC reports purity as the main peak’s share of total peak area, and mass spectrometry confirms identity against the expected molecular weight of 390.3 g/mol. Published certificates are on our COA page, and others are available on request; match the lot number on your vial to the report before use in an experiment.
Related Research Compounds
Laboratories working with Epithalon often also reference: NAD+, MOTS-c.
More Questions About Epithalon
What is the sequence of Epithalon?
Ala-Glu-Asp-Gly (AEDG in single-letter code), a linear tetrapeptide.
Is Epithalon the same as epithalamin?
No. Epithalamin is a pineal gland extract; Epithalon is the synthetic four-residue peptide designed from research on that extract.
Storage and Handling
- Store lyophilized powder at -20°C for long-term storage, protected from light and moisture.
- Short-term storage at 2–8°C is acceptable for unopened vials.
- Allow the vial to reach room temperature before opening to limit moisture uptake.
- Record batch and lot numbers for every preparation.
Frequently Asked Questions
How is the purity of Epithalon verified?
OxygenLab products are tested by independent third-party laboratories for identity and purity (HPLC and mass spectrometry). A certificate for this product is available on request; contact us. Published certificates are on our COA page.
How should lyophilized Epithalon be stored?
Store unopened vials at -20°C, protected from light and moisture. Short-term storage at 2–8°C is acceptable.
Is Epithalon intended for human use?
No. Epithalon is sold strictly for laboratory research use and is not for human or animal consumption.
Related Research Guides
- How to read a peptide certificate of analysis
- What HPLC purity means for research peptides
- How to store lyophilized peptides
Research use only. This product is supplied for in-vitro laboratory research and analytical use only. It is not for human or animal use, and not intended to diagnose, treat, cure or prevent any disease. See our Legal & Compliance policy.
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